Wednesday, September 11, 2013
Wednesday, July 31, 2013
Prairie paintings
Thursday, March 28, 2013
Benefit for
5 à 7 le 9 avril
Admission $10
Concert, bar payant et bouchons
Griffintown Café
1378 rue Notre Dame ouest
Et vente de peintures
tous les bénéfices au profit des classes
de « Parkinson en mouvement »
(voir d'autres peintures et liste de prix à
'pandorasboxinthegardenofeden.blogspot.com')
The following paintings will be on show:
Tree, 14x18 inches oil on canvas
stretched , $300
Gulls, 12x14 inches acrylic on
paintboard, $340
Retreat, 10x14 inches watercolour on paper,
$140
Saturday, March 16, 2013
Better control for Parkinson's symptoms
Dosing carbidopa/levodopa in later
Parkinson's disease with motor fluctuations.
After the first five years with
Parkinson's disease, motor fluctuations become common. There are no
longer enough dopaminergic neurones remaining to store the dopamine
from the levodopa doses, and you go from an “off” state to a
“dyskinetic” state over and over during the day. You are either
not moving because there is not enough dopamine, or you are moving
all over the place and tipping yourself off balance from too much.
The very short half life of levodopa is at fault.
Dr. Ahllskog in his book The
Parkinson's Disease Treatment Book (2005, Oxford University Press)
explains how to deal with this.
- Find the dose of levodopa that gets you motor improvement but not dyskinesia. (For some this is not possible because the two responses occur at the same dose.)
- Match the interval doses to the duration of the response. Then reduce the interval between the doses so that the effects overlap. Eg, if you expect to go “off” 3 hours after a dose, and it takes 30 minutes to kick in, you need to take the next dose after 2 1/2 hours. You can take as many doses as you need to to maintain the response.
- I found that the first dose of the day had to be a little higher, because the duration of response to that dose was very short. This is likely due to the fact that while sleeping you tolerate a lower level of dopamine, and so it takes a little more to saturate.
I
ended up with a program of
7am 1
1/2 tabs
9:35
am 1 tab
12:10
pm 1 tab
2:45
pm 1 tab
5:20
pm 1 tab
7:55
pm 1 tab
1 tab
at bedtime and when I wake in the night (usually after 3-5 hours).
And
with that I am “on” all the time (well at least for 3 days)! I
need to evaluate how I do when I am at the gym, since I may need an
extra 1/2 to 1 tablet to prevent fluctuations after workouts. It is
a miracle!
I have
to add that at the same time I am adding a dopamine agonist, but I am
still at a dose of that medication too small to be expected to make a
difference.
Saturday, September 8, 2012
Gladys Mary Spurll, in memorium
her at Christ Church Cathedral in Montreal September 4, 2012. Some of the pictures we showed at the reception following.
On the beach.
With daughter Barbara and grandson Welland.
With daughter Gwen and grandson Henk.
With Jan Dijkman baptizing grandson Geoffrey, grandson Henk in the foreground, daughter Gwen at the side.
With Geoffrey at daughter Barbara's wedding.
On the beach.
In front of one of the churches in the Pembina Hills area.
With her sister Winifred's family. Left to right, daughter Gwen, grandson Henk, Gladys, Winifred and her dog, nephew Stephen, niece Val, and brother-in-law Frank.
With grandson Gem.
Reading at daughter Gwen's wedding.
With daughter Rosemary.
With Henk Sr, and grandson's Gem and Sean.
At daughter Rosemary's wedding.
At daughter Vanessa's wedding.
Christmas dinner with daughters Rosemary and Vanessa, and son David.
Subscribe to:
Posts (Atom)











































